Electroconvulsive therapy. Clinical and basic research issues.

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منابع مشابه

The effect of electroconvulsive therapy on the levels of oxidative stress factors in the prefrontal cortex of depressed rats

Background and Objective: Electroconvulsive therapy (ECT) is one of the effective and less complicated methods for treatment of depression in cases of resistance to common treatments. Given the fundamental role of pre-frontal cortex on changing the mood of depression-related behaviors in depressed patients, the effects of electroconvulsive therapy on enzymatic activity of this cortex were taken...

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The Therapeutic Effect of Electroconvulsive Therapy in Obsessive-Compulsive Disorder Patients: A Quasi-Experimental Study

Background: Electroconvulsive therapy (ECT) is demonstrated to be an effective treatment in some psychiatric disorders. It is postulated ECT should primarily be considered for patients with treatment-resistant obsessive-compulsive disorder (OCD) in the context of major depression. Therefore, we aimed to evaluate the efficacy of ECT in OCD patients without comorbid psychiatric disorders. Method...

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Ameliorative activity of co-administration of ketamine and ECT on depression like behaviors in depressed rats

Background and Objective: Electroconvulsive therapy (ECT) is the end choice treatment for patients with major depressive disorder (MDD). Regarding researches that show NMDA receptor inactivation could yield the same results as anti-depressant drugs, however, the present study examined co-administration of ECT and ketamine (as NMDA antagonist) on depressed rat behaviors.   Materials and Methods...

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Dose-Response Relationship of Clinical Effi-cacy and Side Effects of Electroconvulsive Therapy

Background: The electrical dose selected for electroconvulsive therapy (ECT) must have an acceptable efficacy and no or minimal cognitive side-effects. We evaluated the clinical efficacy and cognitive side-effects of ECT in relation to the stimulus dose administered. Method: This study assessed 71 depressed patients who were treated with bilateral ECT. For evaluation of depressive and cognitive...

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Behavioral function improvement of prefrontal cortex in treated depressed rats by ECT and ketamine

Background and Objective: Depression is one of the most prevalent mental disorders. Electroconvulsive Therapy (ECT) is one of the effective methods for treatment of depression. Regarding the stimulatory effect of glutaminergic system on the progression of depression, the effect of ketamine as one of the most important inhibitors of this system has been investigated on the effectiveness of ECT. ...

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عنوان ژورنال:
  • Annals of the New York Academy of Sciences

دوره 462  شماره 

صفحات  -

تاریخ انتشار 1986